Germany announced record coronavirus fatalities and infections Thursday as the total death toll passed 100,000, with the nation's most severe virus wave worsening just as a new government prepares to replace Angela Merkel's coalition.

Germany weathered earlier bouts of the pandemic better than many other European countries, but has seen a recent resurgence, with intensive care beds rapidly filling up.

Europe's largest economy recorded 351 Covid fatalities in the past 24 hours, bringing the official death toll since the start of the pandemic to 100,119, in what Bild daily called a "grim milestone".

The weekly incidence rate also hit an all-time high of 419.7 new infections per 100,000 people, the Robert Koch Institute health agency said.

The escalating health crisis poses an immediate challenge to the new centre-left-led coalition government of Social Democrats, Greens and liberal Free Democrats set to take over from Merkel's cabinet next month.

The country has been stuck in political limbo since the September 26 general election, with the popular former scientist Merkel governing in a caretaker capacity.

The spike in Germany comes as Europe has re-emerged as the pandemic's epicentre, with the continent battling sluggish vaccine uptake in some nations, the highly contagious Delta variant, colder weather sending people